Alabama Governor Kay Ivey posted on Twitter to warn residents there could be more extreme weather to come.
"Our hearts go out to those who lost their lives in the storms that hit Lee County today," she wrote.
President Donald Trump also tweeted, asking people to "Please be careful and safe".
And Apple CEO Tim Cook, who was born in Mobile in the southwest of the state, said he was "devastated" by the news, saying Lee County was "a place close to my heart".
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